학사과정학과

  • 기계공학과
  • 산업공학과
  • 응용화학생명공학과
  • 화학공학과
  • 신소재공학과
  • 환경안전공학과
  • 건설시스템공학과
  • 교통시스템공학과
  • 건축학과
  • (대학원)시스템공학과
  • 융합시스템공학과

응용화학생명공학과

교수정보의 상세 화면
윤성화
이름
윤성화
학력
박사
전공
응용화학생명공학전공(과)
정보
연구실 :
팔달관 503

연구실번호 :
2515

이메일 :
shyoon@ajou.ac.kr

연구관심분야 :
논문 및 연구활동
연구활동(주요논문)
  • [논문] 이자경, 박주영, 이혜경, 이한비 , 김승우, 윤성화, 김일두 , Anti-Inflammatory and Neuroprotective Effects of DIPOPA (N,N-Diisopropyl-2-Oxopropanamide), an Ethyl Pyruvate Bioisoster, in the Postischemic Brain , NEUROTHERAPEUTICS , Vol.16 , No.2 , pp.523 -537 (May, 2019)
  • [논문] 윤성화, 김주현, Myongjae Lee, 서명원, Jisook Kwon, 김승주, Characterization of Linagliptin–Ferulic Acid Cocrystal with Improved Thermal and Photostability , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.40 , pp.453 -456 (Mar, 2019)
  • [논문] 김욱, 신한호, 박주영, 윤성화, 손동휘, 김기우, 성제경, 한지혜, 노준기, A novel peripheral cannabinoid 1 receptor antagonist, AJ5012, improves metabolic outcomes and suppresses adipose tissue inflammation in obese mice , FASEB JOURNAL , Vol.33 , No.3 , pp.4314 -4326 (Feb, 2019)
  • [논문] 윤성화, 최동국, 김병욱, 박주영, 이해언, Synthesis of Clovamide Analogues That Inhibit NO Production in Activated BV-2 Microglial Cells , BIOLOGICAL & PHARMACEUTICAL BULLETIN , Vol.40 , No.9 , pp.1475 -1482 (Sep, 2017)
  • [논문] 윤성화, 목희연, 곽우영, Improved Synthesis of (R)-3-(t-Butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic Acid as a Key Intermediate for the Synthesis of Sitagliptin , Bulletin of the Korean Chemical Society , Vol.38 , No.8 , pp.976 -979 (Aug, 2017)
국제학술논문지
  • [논문] 이자경, 박주영, 이혜경, 이한비 , 김승우, 윤성화, 김일두 , Anti-Inflammatory and Neuroprotective Effects of DIPOPA (N,N-Diisopropyl-2-Oxopropanamide), an Ethyl Pyruvate Bioisoster, in the Postischemic Brain , NEUROTHERAPEUTICS , Vol.16 , No.2 , pp.523 -537 (May, 2019)
  • [논문] 윤성화, 김주현, Myongjae Lee, 서명원, Jisook Kwon, 김승주, Characterization of Linagliptin–Ferulic Acid Cocrystal with Improved Thermal and Photostability , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.40 , pp.453 -456 (Mar, 2019)
  • [논문] 김욱, 신한호, 박주영, 윤성화, 손동휘, 김기우, 성제경, 한지혜, 노준기, A novel peripheral cannabinoid 1 receptor antagonist, AJ5012, improves metabolic outcomes and suppresses adipose tissue inflammation in obese mice , FASEB JOURNAL , Vol.33 , No.3 , pp.4314 -4326 (Feb, 2019)
  • [논문] 윤성화, 최동국, 김병욱, 박주영, 이해언, Synthesis of Clovamide Analogues That Inhibit NO Production in Activated BV-2 Microglial Cells , BIOLOGICAL & PHARMACEUTICAL BULLETIN , Vol.40 , No.9 , pp.1475 -1482 (Sep, 2017)
  • [논문] 윤성화, 목희연, 곽우영, Improved Synthesis of (R)-3-(t-Butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic Acid as a Key Intermediate for the Synthesis of Sitagliptin , Bulletin of the Korean Chemical Society , Vol.38 , No.8 , pp.976 -979 (Aug, 2017)
  • [논문] 윤성화, 박주영, 최규진, 이자경, 김승우, Neuroprotective effect of triflusal and its main metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid (HTB), in the postischemic brain , NEUROSCIENCE LETTERS , Vol.643 , pp.59 -64 (Mar, 2017)
  • [논문] 윤성화, 박주영, 이혜경, 이자경, 김승우, 이한비, 김일두, Anti-inflammatory and antiexcitoxic effects of diethyl oxopropanamide, an ethylpyruvate bioisoster, exert robust neuroprotective effects in the postischemic brain , SCIENTIFIC REPORTS , Vol.7 , pp.42891 -42891 (Feb, 2017)
  • [논문] 이자경, 박주영, 김승우, 김일두, 이한비, Lidan Luo, 윤성화, 이혜경, Robust neuroprotective effects of 2-((2-oxopropanoyl)oxy)-4-(trifluoromethyl)benzoic acid (OPTBA), a HTB/pyruvate ester, in the postischemic rat brain , SCIENTIFIC REPORTS , pp.1 -12 (Aug, 2016)
  • [논문] 이자경, 김현지, 이혜경, 윤성화, 김승우, Neuroprotective effect of ethyl pyruvate against Zn2+ toxicity via NAD replenishment and direct Zn2+ chelation , NEUROPHARMACOLOGY , Vol.105 , pp.411 -419 (Jun, 2016)
  • [논문] 최용문, 박주영, 권순정, 구진모 , 박규희, 이정훈, 안상미, 정대연, 양준근, 조경진, 김유한, 남태규, 윤성화, 남연주, Discovery, Optimization, and Biological Evaluation of Sulfonamidoacetamides as an Inducer of Axon Regeneration , JOURNAL OF MEDICINAL CHEMISTRY , Vol.59 , No.10 , pp.4676 -4687 (May, 2016)
  • [논문] 윤성화, 최동국, 이자경, 김병욱, 박주영, 권순정, Syntheses of Ethyl Pyruvate’s Bioisosteres Inhibiting Inducible Nitric Oxide Production in Lipopolysaccharide-induced BV2 Cells , LETTERS IN DRUG DESIGN & DISCOVERY , Vol.12 , No.7 , pp.591 -596 (Jul, 2015)
  • [논문] 윤성화, 박주영, 김병욱, Sushruta Koppula, Hemant Kumar, 김시관, 최동국, 김일웅, 김인수, 한상돈, Sandeep Moore, alpha-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease , NEUROPHARMACOLOGY , Vol.97 , pp.46 -57 (May, 2015)
  • [논문] 윤성화, 박주영, 임형우, 박정인, 최동국, 김병욱, 윤요셉, 박은정, 전세봄, Sandeep More, Anti-neuroinflammatory effects of DPTP, a novel synthetic clovamide derivative in in vitro and in vivo model of neuroinflammation , BRAIN RESEARCH BULLETIN , Vol.112 , pp.25 -34 (Mar, 2015)
  • [논문] 최동국, 박주영, 민순, 박은정, 박신영, 전세범, 윤성화, Sandeep Vasant Moore, EOP, a Newly Synthesized Ethyl Pyruvate Derivative, Attenuates the Production of Inflammatory Mediators via p38, ERK and NF-κB Pathways in Lipopolysaccharide-Activated BV-2 Microglial Cells , MOLECULES , Vol.19 , No.12 , pp.19361 -19375 (Nov, 2014)
  • [논문] 최동국, 박주영, 박정인, Sandeep Vasant Moore, 김병욱, 윤성화, 강성묵, A novel synthetic HTB derivative, BECT inhibits lipopolysaccharide-mediated inflammatory response by suppressing the p38 MAPK/JNK and NF-κB activation pathways , PHARMACOLOGICAL REPORTS , Vol.66 , No.3 , pp.471 -479 (Jun, 2014)
  • [논문] 윤성화, 신영균, 권영배, 박주영, 김기원, Syntheses of 7-Substituted α-Cyperone Derivatives for Selective Sigma-1 Receptor over Cannabinoid-1 Receptor Binding Affinities , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.34 , No.11 , pp.3499 -3502 (Nov, 2013)
  • [논문] 이자경, 박주영, 김일두, 김승우, Yinchuan Jin, 윤성화, 이혜경, Anti-inflammatory effects of OBA-09,a salicylic acid/pyruvate ester,in the postischemic brain , BRAIN RESEARCH , Vol.1528 , pp.68 -79 (Aug, 2013)
  • [논문] 최동국, 박주영, Sandeep Vasant More, Sushruta Koppula, Hemant Kumar, 임형우, 강성묵, 윤성화, 깁병욱, Anti-neuroinflammatory Activity of a Novel Cannabinoid Derivative by Inhibiting the NF-κB Signaling Pathway in Lipopolysaccharide Induced BV-2 Microglial Cells , JOURNAL OF PHARMACOLOGICAL SCIENCES , pp.119 -130 (Feb, 2013)
  • [논문] 윤성화, 명승윤, 최동국, 김인수, 박주영, 권순정, Simultaneous Measurement of Serotonin, Dopamine and Their Metabolites in Mouse Brain Extracts by High-Performance Liquid Chromatography with Mass Spectrometry Following Derivatization with Ethyl Chloroformate , BIOLOGICAL & PHARMACEUTICAL BULLETIN , Vol.36 , No.2 , pp.252 -258 (Feb, 2013)
  • [논문] 권정환, 장희라, 이은화, 김균, 이현정, 윤성화, Enzymatic and microbial transformation assays for the evaluation of the environmental fate of diclofenac and its metabolites , CHEMOSPHERE , Vol.87 , No.8 , pp.969 -974 (May, 2012)
  • [논문] 진병관, 박주영, 정영철, 복유진, 김상열, 김윤성, 맹성호, 박성현, 윤성화, 허수현, Cannabinoid Receptor Type 1 Protects Nigrostriatal Dopaminergic Neurons against MPTP Neurotoxicity by Inhibiting Microglial Activation , JOURNAL OF IMMUNOLOGY , No.12 , pp.6508 -6517 (Dec, 2011)
  • [논문] 도경오, 윤성화, 이수진, Enhancement of Gene Delivery Using Novel Homodimeric Tat Peptide Formed by Disulfied Bond , JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY , Vol.21 , No.8 , pp.802 -807 (Aug, 2011)
  • [논문] 윤성화, 김승우, 이자경, 김현지, A simple and sensitive high performance liquid chromatography-electrospray ionization/mass spectrometry method for the quantification of ethyl pyruvate in rat plasma , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.32 , No.4 , pp.1221 -1227 (Apr, 2011)
  • [논문] 윤성화, 진병관, 김승우, 이자경, 박주영, 임원빈, Simplified Heterocyclic Analogues of Fluoxetine Inhibit Inducible Nitric Oxide (NO) Production in Lipopolysaccharide (LPS)-Induced BV2 Cells , Biological and Pharmaceutical Bulletin , Vol.34 , No.4 , pp.538 -544 (Apr, 2011)
  • [논문] 진병관, 박주영, 정영찬, 김상열, 정은숙, 김윤성, 원소연, 복의진, 진민영, 박은수, 고혁운, 윤성화, 박근우, Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation , NEUROPHARMACOLOGY , Vol.60 , pp.963 -974 (Apr, 2011)
  • [논문] 윤성화, John Finn, 최선호, 최성학, 임원빈, 박주영, Discovery of Torezolid as a Novel 5-Hydroxymethyl-Oxazolidinone Antibacterial Agent , EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY , Vol.46 , pp.1027 -1039 (Feb, 2011)
  • [논문] 이자경, 김현지, 김승우, 김일두, 이정은, 한평림, 윤성화, 신주현, Robust protective effects of a novel multimodal protectant oxopropanoyloxy benzoic acid (a salicylic acid/pyruvate ester) in the postischemic brain , MOLECULAR PHARMACOLOGY , Vol.79 , No.2 , pp.220 -228 (Feb, 2011)
  • [논문] 윤성화, 김승우, 박호준, 이자경, 박주영, 임원빈, Synthesis and Antioxidant Effect of Caffeic Acid Analogues Bearing a Carboxy and Hydroxymethyl Group , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.31 , No.12 , pp.3860 -3863 (Dec, 2010)
  • [논문] 윤성화, 김상현, 권정환, An improved synthesis of 4'-hydroxydiclofenac , BULLETIN OF THE KOREAN CHEMICAL SOCIETY , Vol.31 , No.10 , pp.3007 -3009 (Oct, 2010)
  • [논문] 서해영, 장다영, 유승완, 홍영태, 김세중, 김수정, 백선아, 이영돈, 김성수, 윤성화, 조경기, The growth of brain tumors can be suppressed by multiple transplantation of mesenchymal stem cells expressing cytosine deaminase , INTERNATIONAL JOURNAL OF CANCER , Vol.127 , No.8 , pp.1975 -1983 (Oct, 2010)
  • [논문] 진병관, 박주영, 정은숙, 박은수, 복유진, 백형후, 윤성화, 정영철, Fluoxetine prevents LPS-induced degeneration of nigral dopaminergic neurons by inhibiting microglia-mediated oxidative stress , BRAIN RESEARCH , No.1363 , pp.143 -150 (Sep, 2010)
  • [논문] 윤성화, 손문호, 김하동, 채유나, 신창열, 김순회, 안국준, 최성현, 양은경, 박경진, 채혜원, 문호상, 신영균, 김미경, Peripherally acting CB1-receptor antagonist: the relative importance of central and peripheral CB1 receptors in adiposity control , INTERNATIONAL JOURNAL OF OBESITY , No.34 , pp.547 -556 (Mar, 2010)
  • [논문] 이자경, 김현지, 서지선, 정지영, 한평림, 윤성화, 김승우, Combination treatment of ethyl pyruvate and aspirin enhances neuroprotection in the postischemic brain , NEUROTOXICITY RESEARCH , No.17 , pp.39 -49 (Jan, 2010)
  • [논문] 이창호, 윤영실, 민철기, 윤성화, 조태섭, N-Methylamine substituted fluoxetine derivatives:New dopamine transporter inhibitors , ARCHIVES OF PHARMACAL RESEARCH , Vol.32 , No.12 , pp.1663 -1671 (Dec, 2009)
  • [논문] 류종훈, 김동현, 이승주, 윤성화, Sub-chronic administration of rimonabant causes loss of antidepressive activity and decrease doublecortin immunoreactivity in the mouse hippocampus , Neuroscience letters , Vol.467 , No.2009 , pp.111 -116 (Dec, 2009)
  • [논문] 윤성화, 신영균, New One-Pot Synthesis of 4-Hydroxybenzaldehyde Derivatives and Picric Acid from 4-Hydroxyphenylglycine with HNO3/H2O , Bulletin of the Korean chemical society , Vol.30 , No.11 , pp.2819 -2822 (Nov, 2009)
  • [논문] 이자경, 한평림, 진인찬, 김승우, 서지원, 임채문, 윤성화, 박주영, Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus , Brain research , Vol.2009 , No.1281 , pp.108 -116 (Jun, 2009)
  • [논문] 이자경, 임채문, 김승우, 김채균, 윤성화, 박주영, Fluoxetine affords robust neuroprotection in the postischemic brain via its anti-inflammatory effect , Journal of Neuroscience Research , Vol.87 , No.4 , pp.1037 -1045 (Feb, 2009)
  • [논문] 윤성화, 정효재, 신영균, 김영수, 박호준, Bioisoster of caffeic aicd: Syntheses of 1-hydroxy-2-pyridone analogues , BULLETIN of the Korean Chemical Society , Vol.29 , No.11 , pp.2277 -2280 (Nov, 2008)
  • [논문] 윤성화, 신영균, 이해언, 박호준, A new route of 5-(N-phenetylamino)salicylic acid derivatives by rapid and selective reduction of the amide group with NaBH4/acetic acid , Synthetic Communications , Vol.38 , No.11 , pp.1822 -1829 (May, 2008)
  • [논문] 윤성화, 이자경, 김승우, 박호준, 신영균, Suk Bin Kong, 김윤정, New peptidic neuroprotectas against NMDA neurotoxicity: Syntheses and biological evaluations of linear complestatin analogs , LETTERS IN DRUG DESIGN & DISCOVERY , Vol.5 , No.2 , pp.104 -107 (Mar, 2008)
  • [논문] 윤성화, 신영균, 박상후, 박호준, Bicholas Bodor, Jiaxaing Wu, Selective reduction of trigonellyl group to the corresponding dihydropyridine in the presence of disulfide group , Bulletin of the Korean Chemical Society , Vol.29 , No.2 , pp.479 -482 (Feb, 2008)
  • [논문] 곽병주, 안영민, 문호상, 이해운, 고선영, 권혜진, 김기원, 노지현, 박선미, 변한열, 손선주, 원석준, 윤복선, 이문정, 이영애, 이지윤, 임두순, 임향란, 정준모, 조성익, 조제영, 윤성화, Marked prevention of ischemic brain injury by Neu2000, an NMDA antagonist and antioxidant derived from aspirin and sulfasalazine , Journal of Cerebral Blood Flow and Metabolism , Vol.2007 , No.27 , pp.1142 -1151 (Jun, 2007)
  • [논문] 곽병주, 정준모, 주천기, 최춘섭, 원석준, 유보름, 이영애, 장수현, 윤성화, 노지현, The Novel Neuroprotective Action of Sulfasalazine through Blockade of NMDA Receptors , The Journal of Pharmacology and Experimental Therapeutics , Vol.305 , No.1 , pp.48 -56 (Mar, 2003)
  • [논문] 김수동, 문호상, 남성일, 이영애, 곽병주, 김동현, 윤성화, Structural requirements for the neuroprotective effects of aspirin analogues against N-methyl-D-aspartate and zinc ion neurotoxicity , JOURNAL OF PHARMACY AND PHARMACOLOGY , pp.935 -944 (Jul, 2002)
  • [논문] 윤성화, 이영애, 남성일, 문호상, 김동연, 김수동, Structural requirements for the neuroprotective effects of aspirin analogues against N-methyl-D-aspartate and zinc ion neurotoxicity , Journal of Pharmacy and Pharmacology , Vol.54 , No.7 , pp.935 -944 (Jul, 2002)
  • [논문] Nicholas Bodor, Jiaxiang Wu, Whei-Mei Wu, 윤성화, Synrthesis and biological evaluation of brain-targeted chemical delivery systems of [Nva2]-TRH , Journal of Pharamcy and Pharmacology , Vol.54 , No.7 , pp.945 -950 (Jul, 2002)
  • [논문] 윤성화, Jiaxiang Wu, Nicholas Bodor, Synthesis and Brain Targeted Delivery of [Nva2,Pip3]-TRH , Bulletin of the Korean Chemical Society , Vol.23 , No.5 , pp.761 -764 (May, 2002)
  • [논문] 윤성화, 정준모, 한평림, 장수연, 강규완, 김은영, 유보름, 문호상, Attenuation of Zn2+ Neurotoxicity by Aspirin: Role of N-Type Ca2+ Channel and the Carboxyl Acid Group , Academic Press , Vol.8 , pp.774 -783 (Oct, 2001)
  • [논문] 곽병주, 한평림, 문호상, Chang Su-Youne, 강규완, 김은영, Bo Rum Ryu, Choun-Ki Joo, 윤성화, Attenuation of Zn2+ NeuroToxicity by Aspirin: Role of N-Type Ca2+ Channel and the Carboxyl Acid Group , Neurobiology of Disease , Vol.8 , pp.744 -783 (May, 2001)
  • [논문] Nicholas Bodor, Whei-Mei Wu, Jiaxiang Wu, 윤성화, Laszlo Prokai, Brain-Targeted Chemical Delivery of [Leu2,Pip3]-TRH; Synthesis and Biological Evaluation , Pergamon Press , Vol.8 , No.5 , pp.1059 -1063 (Jun, 2000)
  • [논문] Nicholas Bodor, 황성관, Atilla Juhasz, 윤성화, Soft Drug 12: Design, Synthesis, and Evaluation of Soft Bufuralol Analogues , American Chemical Society , Vol.43 , No.8 , pp.1525 -1532 (Apr, 2000)
  • [논문] 윤성화, 김현숙, Bioisoster of Capsaicin: Synthesis of 1-Hydroxy-2-pyridone Analogue , Bulletin of the Korean Chemical Society , Vol.20 , No.7 , pp.857 -859 (Jul, 1999)
  • [논문] 윤성화, 황성관, 이영희, 김동연, 서승기, Syntheses of 2-[(3,5-Dimethyl-4-Methoxypyridyl)alkyl)benzothiazodine Derivatives As a Potential Gastric H+/K+-ATPase Inhibitor , 영국화학회 , Vol.8 , pp.1909 -1912 (Sep, 1998)
  • [논문] 윤성화, 황성관, 최승룡, 강성구, 문호상, Syntheses and Cytotoxicities of Four Stereoisomers of Muricatacin from D-Glucose , Bioorgaic and Medicinal Chemistry , Vol.6 , pp.1043 -1049 (Aug, 1998)
  • [논문] 박규순, 이윤석, 이석우, 윤성화, 최승룡, Synthesis of Optically Pure (2R,2'R,5R,5'R)-5,5'-Bisiodomethyl-octahydro[2,2']-bifuran from Diethyl D-tartrate: Iodoetherification of (5R,6R)-5,6-Dihydroxy-1,9-decadiene , Bulletin of the Korean Chemical Society , Vol.19 , No.1 (Jan, 1998)
  • [논문] 윤성화, 윤병선, 이재의, 강봉구, 서문호, 이석현, Studies on the Physical properties of Modified Starch-filled HDPE Film , Journal of Applied Polymer Science , Vol.60 , pp.1977 -1984 (Mar, 1996)
  • [논문] 서문호, 정시화, 이재의, 윤병선, 윤성화, 이석현, Studieson the Degradable Polyethyles : Use of Coated Photodegradants with Biopolymers , Journal of Applied Polymer Science , Vol.60 , pp.1677 -1685 (Mar, 1996)
  • [논문] 이우영, 김효중, 심원보, 윤성화, Biscyclophanes. Part 2:Regioselectivity in the Acid-Catalysed Cycloalklation of Benzylbenzylic Alcohol(BBA) , J.of Chem.Soc.Perkin Trans.(SCI) , pp.719 -729 (Mar, 1993)
  • [논문] Nicholas, James.W.S., 윤성화, Synthesis and In Vitro Dopaminergic Activity of (2-Aminoethly)-1-hydroxy-2-pyridone Type Dopamine Analogs , Drug Design and Discovery , Vol.10 , pp.35 -43 (Mar, 1993)
국내학술논문지
  • [논문] 김영수, 김수동, 윤성화, Effect of Softcapsule Fill Formulation on the Stability and the Disintegration Time of Ginkgo Biloba Extract , Jouranl of Korean Industrial Engineering Chemistry , Vol.10 , No.6 , pp.848 -851 (Oct, 1999)
  • [논문] 김영수, 김수동, 윤성화, 연질캅셀 제제 처방이 은행잎 엑스의 안정성 및 붕해 시간에 미치는 영향 , 공업화학 , Vol.10 , No.6 , pp.848 -851 (Aug, 1999)
  • [논문] 윤성화, 박정하, 김영수, 문호상, A New Route to the Synthesis of Cortodoxon from Progesterone , Bulletin of the Korean Chemical Society , Vol.20 , No.2 , pp.229 -231 (Feb, 1999)
  • [논문] 윤성화, 문호상, 강석구, Synthesis and Cytotoxicity of (-)-(4R,5R)-5-C-(11-Methoxy)muricatacin , Bulletin of the Korean ChemicalSociety , Vol.19 , No.9 , pp.1016 -1018 (Sep, 1998)
  • [논문] 윤성화, 김도영, 황성관, Synthesis of N-[2-(3,5-dimethyl-4-methoxypyridyl)alkyl]oxazolidinone Analogues and Evaluation of Their Proton Pump Enzyme Inhibition , J. of Korean Pharmaceutical Society , Vol.41 , No.2 , pp.174 -180 (Apr, 1997)
  • [논문] 윤성화, 황성관, 심원보, Efficient Synthesis of 2-Acetyl-7-formylbenzofuran and 2-Acetyl-(formylmetyl)benzofuran through the Oxidative Cleavage of Allybenzofuran with Osmium Tetraoxide/Sodium Periodate , Bull. Korean Chemical Society , Vol.17 , No.3 , pp.295 -299 (Mar, 1996)
  • [논문] 윤성화, 박규순, Synthesis & in Vitro Stability Evaluation of 5-(2'-(N-(1-methyl-3'-carbamylphenyl)-n-propyl))aminoethyl)-8-hydroxy-4-methyl carbostyril Deravatives , 약학회지 , Vol.39 , No.5 , pp.506 -510 (Mar, 1995)
  • [논문] 윤성화, 유경수, 김영희, Synthesis and Characterization of Poly[5,6-dideoxy-alpha-D-xylo-hex-5-enofuranose-alt(maleic anhydride)] , Bull.Korean.Chem.Soc , Vol.15 , No.5 , pp.407 -410 (Mar, 1994)
  • [논문] 윤성화, 신약도안에서의 Biosoterism의 응용 , 화학세계 , Vol.33 , No.8 , pp.576 -579 (Mar, 1993)
국제학술발표
  • [학술회의] 김욱, 윤성화, 김은하, 김정은, 윤주환, Characterization of AJ5012 as a Novel Peripheral Cannabinoid 1 Receptor Antagonist in Mouse Models of Obesity , 78th Scientific Sessions of American Diabetes Association (Jun, 2018)
  • [학술회의] 김욱, 노준기, 윤성화, 윤주환, 허성은, 한지혜, 신한호, Blockade of peripheral cannabinoid 1 receptor attenuates insulin resistance through inhibition of NLRP3 inflammasome activation in diabetic obese mice , 77th Scientific Session of American Diabetes Association (Jun, 2017)
  • [학술회의] 김욱, 윤성화, 신한호, 박주영, 한지혜, 노준기, Blockade of peripheral cannabinoid 1 receptors improves insulin resistance through preventing the activation of NLRP3 inflammasome in white adipose tissue , 2016 Internationbal Congress on Obesity and Metabolic Syndrome in conjunction with the 45th Annual Scientific Meeting of KSSO (Sep, 2016)
  • [학술회의] 윤성화, 박정호, 최동국, 박주영, 권순정, Synthesis and bioogical evaluation of caffeic acid analogues for antioxidant activities , 2012 Proceedings of International Congress of Korean Fedration of Pharmaceutical Societies , pp.329 -329 (Apr, 2012)
  • [학술회의] 윤성화, 박성훈, 최동국, 이은화, Synthesis and Biological Evaluation of 3-Morpholino-1-phenylpropan-1-one Analogues as an Inhibitor of Inducible Nitric Oxide Production in Lipopolysaccharide-Induced BV2 Cells , 2011 대한약학회 추계 국제학술회의 , pp.250 -250 (Nov, 2011)
  • [학술회의] 윤성화, 이자경, 박성훈, 김승우, 박주영, 이은화, Synthesis and antioxidant effect of caffeic acid analogues bearing a carboxy and hydroxymethyl group , the Fall International Convention of the Pharmaceutical Society of Korea , pp.210 -210 (Oct, 2010)
  • [학술회의] 윤성화, 권정환, 박성훈, 김상현, An improved procedure for preparation of 4'-hydroxydichlorofenac , Proceedings of the spring international convention of the pharmaceutical society of korea (Apr, 2010)
  • [학술회의] 윤성화, 김승우, 이자경, 김현지, 이은화, Neuroprotective effects of ethyl pyruvate derivatives by transition metal chelation , The proceedings of the spring international convention of the pharmaceutical society of Korea (Apr, 2010)
  • [학술회의] 윤성화, 김현지, 이자경, Retrometaboic approach for the treatment of stroke based on pyruvylsalicylic acid system , 7th Retrometabolic Based Drug Design and Targeting Conference , Vol.2009 , No.1 , pp.23 -23 (May, 2009)
  • [학술회의] 윤성화, 박주영, Synthesis and biological evaluation of oxoacetamide analogues of rimonabant as CB1 cannabionoid receptor ligands , Medicianl chemistry conference (lead optimization and lead discovery) , Vol.2009 , pp.31 -31 (Feb, 2009)
  • [학술회의] 이자경, 최경신, 신주현, 임채문, 윤성화, 김승우, Multi-mechanism baded ethyl pyruvate hybrid compound affords robust neuroprotection in the postischemic brain , Annual meeting of neuroscience 2008 , Vol.2008 , pp.97 -97 (Nov, 2008)
  • [학술회의] 윤성화, 정효재, 박호준, 박정호, 박상후, Bioisosteres of Caffeic Acid: Syntheses of 1-Hydroxy-2-Pyridone Analogs , 대한약학회 2008 제주국제학술대회 , Vol.2008 , pp.262 -262 (May, 2008)
  • [학술회의] 윤성화, 임원빈, 박주영, Measurement of Dopamine, Their Metabolites and Serotonin by High Performance Liquid Chromatography with Mass Spectrometry Following Derivatization with Ethyl Chloroformate , 대한약학회 2008 제주국제학술대회 , Vol.2008 , pp.307 -307 (May, 2008)
  • [학술회의] 윤성화, 김현지, 이수진, 신영균, Method for Quantification of Ethyl Pyruvate by Liquid Chromatography/Electtospray Ionization Mass Spectrometry , 대한약학회 2008 제주국제학술대회 , Vol.2008 , pp.313 -313 (May, 2008)
  • [학술회의] 이자경, 이해언, 암채문, 김승우, 신주현, 윤성화, 정효재, The synergistic neuroprotection by ethyl pyruvate and apirin in the postischemic brain , the Annual meeting of the society for neuroscience , Vol.2007 , pp.380 -380 (Nov, 2007)
  • [학술회의] 윤성화, 김희연, 정효재, 김현지, Synthesis and biological evaluations of carbamoyl oxime analogs of the cannabinoid receptor-1 (CB1) antagonist SR141716 , 234th Annual Meeting of American Chemical Society , Vol.2007 , pp.34 -34 (Aug, 2007)
  • [학술회의] 윤성화, 신영균, 박주영, 김기원, 김희연, Synthesis and biological evaluations of the cyperone analogs , The 12th Asian symposium on medicinal plants, spices, and natural products , Vol.2006 , No.1 , pp.53 -53 (Nov, 2006)
  • [학술회의] 윤성화, 문호상, 신영균, 곽병주, 박호준, Synthesis and biological evaluations of N-substituted aminosalicylic acid serivatives as novel neuroprotectant agent , 11th Asian Chemical Congress , Vol.11 , No.1 , pp.177 -177 (Aug, 2005)
  • [학술회의] 윤성화, 이재우, 박호준, 곽병주, 이영애, Synthesis and neuroprotective effect of Neu2000 against rat transient ischemic stroke models , 229th Annual Meeting of American Chemical Society , Vol.229 , No.1 , pp.202 -202 (Mar, 2005)
  • [학술회의] 윤성화, 이재우, 이주영, 신영균, New Synthetic method of 3-substituted 4-hydroxy-5-nitrobenzaldehyde and 2-substituted-4,6-dinitrophenol from 3-substituted D-4-hydroxyphenylglycine , 229th Annual Meeting of American Chemical Society , Vol.229 , No.1 , pp.519 -519 (Mar, 2005)
  • [학술회의] 윤성화, 이주영, 박주영, 곽병주, 이영애, Synthesis and biological evaluation of salicylic acid analogues of celecoxib as a new class od selective cyclooxygenase-1 inhibitors , 229th Annual Meeting of American Chemical Society , Vol.219 , No.1 , pp.222 -222 (Mar, 2005)
  • [학술회의] 곽병주, 주인수, 임향란, 박호준, 신진희, 전정욱, 윤성화, 조성익, Neu2000, a new compound with strong antioxidant action and NMDA antagonism, is beneficial against ALS model mice. , Society for Neuroscience 34th Annual Meeting , Vol.34 , No.1 , pp.126 -126 (Oct, 2004)
  • [학술회의] 곽병주, 안춘산, 원석준, 조성익, 임두순, B.S Yoon, J.Y Lee, 강순철, 고선영, 윤성화, 신영균, Neu2000, a novel compound, shows potent neuroprotection against rat ischemic stroke models through multiple mechanisms with wide therapeutic time window , Society for Neuroscience 34th Annual meeting , Vol.34 , No.1 , pp.126 (Oct, 2004)
  • [학술회의] 곽병주, 정준모, 이영애, 권혜진, 노지현, 윤성화, J.Y Lee, NOVEL NEUROPROTECTANT PREVENTING NMDA-, FREE RADICAL-, AND ZINC-NEUROTOXICITY , Society for neuroscience 34th annual meeting , Vol.34 , No.1 , pp.126 -126 (Oct, 2004)
  • [학술회의] 박기동, 지경수, 박형달, 윤성화, 신정욱, 이진우, Chondrogenic Differentiation of a Mesenchymal Stem Cell using a Novel Injectable Thermosensitive Chitosan , 8th Pacific Polymer Conference , pp.1 -3 (Nov, 2003)
  • [학술회의] 윤성화, 박호준, 이해언, 곽병주, Synthesis and neuroprotective effects of the cyclic analogs of complestatin , 226th ACS national meeting , pp.291 -291 (Sep, 2003)
  • [학술회의] 윤성화, 박의진, 원석준, 곽병주, Involvement of mitochondrial reactive oxygen species in the selective vulnerability of somatostatinergic interneurons to kainate , 32nd annual meeting of society for neuroscience , pp.1 -1 (Nov, 2002)
  • [학술회의] 윤성화, 전보형, 박호준, 곽병주, 남상돈, Syntheses and neuroprotective effects of complestatin analogs , 223rd ACS national meeting , Vol.2002 , pp.48 -48 (Apr, 2002)
  • [학술회의] 윤성화, 전보형, 강규완, 박호준, 곽병주, 문호상, Syntheses and Multiple Neuroprotective Effects of Benzylaminosalicylic Acid Derivatives , 222nd ACS National Meeting , Vol.2001 , pp.60 (Aug, 2001)
  • [학술회의] 윤성화, 남상돈, 김윤정, 김정숙, 곽병주, 김상남, Syntheses and Neuroprotective Effects of the Conjugates of 5-(Pentafluorobenzyl)amino Acid with DMVD-FMK Derivatives , 222nd ACS national Meetings , Vol.125 , pp.50 -50 (Aug, 2001)
  • [학술회의] 진병관, 김승업, 류재규, 오영준, 김진, 곽병주, 윤성화, A Novel Neuroprotectant Rescuing Nigral Dopaminergic Neurons From MPP+ Neurotoxicity. , Society for Neuroscience 30th Annual Meeting , Vol.26 , No.857.10 , pp.2282 -2282 (Nov, 2000)
  • [학술회의] 곽병주, 정준모, 장수연, 유보름, 노지현, 윤성화, 이영애, Multiple Neuroprotective Effects of Sulfasalazine Against NMDA, Free Radicals and Zinc. , Society for Neuroscience 30th Annual Meeting , Vol.26 , No.377.13 , pp.1013 -1013 (Nov, 2000)
  • [학술회의] 윤성화, 안영민, 유보름, 이영애, 문호상, 원석준, 곽병주, 안정현, A Novel Neuroprotectant Preventing NMDA-, Free Radical-, and Zinc-neurotoxicity. , Society for Neuroscience 30th Annual Meeting , Vol.26 , No.377.14 , pp.1013 -1013 (Nov, 2000)
  • [학술회의] 윤성화, 문호상, 김수동, 곽병주, Nam seongil, Syntheses and Neuroprotective Effects of Aspirin Analogs , 220th Amnerican Chemical Society National Meeting , pp.219 (Aug, 2000)
  • [학술회의] 윤성화, 황성관, K. Tatrai-Prokai, N. Bodor, A. Juhasz, Soft Analogues of Bufuralol: Initial Pharmacological Evaluation , 14th Annual Scinentific Meeting of American Society of Hypertension , Vol.12 , No.4 , pp.114A -114A (May, 1999)
  • [학술회의] Emy Wu, J. Wu, N. Bodor, 윤성화, L. ProKai, Synthesis and Pharmacological Evaluation of a Brain-Targeted Chemical Delivery System of [Leu2, Pip3]-TRH , PharmaceuticalResearch , Vol.14 , No.11 (Nov, 1997)
  • [학술회의] 윤성화, 황성관, 최승룡, 서승기, 이영희, Syntheses of 2-(3,5-Dimethyl-4-methoxypyridyl)benzothiazolidine Derivatives As A Potential H+/K+-ATPase Inhibitors , Abstract of 213th ACS Natioanl Meeting , Vol.1997 , pp.133 -133 (Apr, 1997)
국내학술발표
  • [학술회의] 김욱, 한지혜, 노준기, 윤성화, 허성은, 이은영, 박주영, 신한호, 윤주환, Blockade of peripheral cannabinoid 1 receptors improves adipose inflammation, hepatic steatosis, and insulin resistance , 제2회 생화학분자생물학회 에너지대사 연구분과 심포지엄 (Jun, 2016)
  • [학술회의] 권정환, 김균, 윤성화, 장희라, 이현정, 이은화, 효소분해시험과 미생물분해시험을 연계한 디클로페낙 및 대사산물의 환경거동평가 , 2011 대한환경공학회 국내 학술대회 (Aug, 2011)
  • [학술회의] 권정환, 윤성화, 김균, 이은화, 장희라, 이현정, 박성훈, Microbial deconjugation of diclofenac glucuronide, a major phase II metabolite of diclofenac , 2010 환경독성보건학회 추계학술대회 (Nov, 2010)
  • [학술회의] 윤성화, 김정숙, 박호준, Rapid and selective reduction of the aromatic amide group by sodium acyloxyborohydride in the pesence of the aromatic ester group , 대한화학회 제 94회 총회 및 학술발표회 , Vol.94 , No.1 , pp.378 (Oct, 2004)
  • [학술회의] 윤성화, 이주영, 신영균, New Method for synthesizing 3-substituted-4-hydroxy-5-nitrobenzaldehyde from 3-substituted-D-4-hydroxyphenylglycine , 대한화학회 제 94회 총회 및 학술발표회 , Vol.94 , No.1 , pp.378 -378 (Oct, 2004)
  • [학술회의] 김철, 김승현, 윤성화, 초임계 유체를 이용한 Peptide의 효소합성(II) , 2000 가을 학술대회 , pp.3765 -3768 (Oct, 2000)
  • [학술회의] 김철, 김승현, 윤성화, 초임계 유체를 이용한 Peptide의 효소합성 , 2000 봄 학술대회 , pp.1221 -1224 (Apr, 2000)
  • [학술회의] 윤성화, 황성관, Attila Yuhasz, Syntheses, Satabilities and Biological Evaluations of Soft Bufuralol Analogues , 83rd Annual Meeting of the Korean Chemical Society , Vol.1999 , pp.228 -228 (Apr, 1999)
  • [학술회의] 윤성화, Nicholas Bodor, Target Brain Delivery of Peptide Analogues: Syntheses and Brain Delivery of TRH Analogues , 제 1회 한국 펩타이드 심포지움 , Vol.1 , No.1 , pp.9 (Nov, 1997)
  • [학술회의] 윤성화, 황성관, 문호상, Syntheses and Cytotoxicities of Four Stereoisomers of Muricatacin and It's Analogues , Abstract of Annual Convention, 1997 , Vol.1997 , pp.385 -385 (Oct, 1997)
  • [학술회의] 윤성화, 김수동, Pharmaceutical Formulation For Enhanced Bioavailability Of Ginkgobiloba Extract , Abstract of Annual Meeting , Vol.1997 , pp.352 -352 (Oct, 1997)
  • [학술회의] 윤성화, 황성관, 박장하, Concise Synthesis of Substance S from Progesterone , 77회 춘계 대한화학회 논문 초록집 , pp.120 -120 (May, 1996)
  • [학술회의] 윤성화, 서승기, 박상후, Synthesis and Biological Evaluation of 2-(3,5-Dimethyl-4-methoxypyridyl)-benzothiazolines as a Novel class of Gasteric H/K-ATPase inhibitors , 춘계 대한약학회 초록집 , pp.120 -120 (Apr, 1996)
  • [학술회의] 박규순, 최승룡, 양재영, 윤성화, Synthetic Studies of 2,5-Disubstituted Bistetrafuran (Oct, 1995)
  • [학술회의] 김동연, 배은형, 윤성화, Synthesis of Pyrazolo-3-(H)-Quinolone Derivatives as (H+/K+)ATPase , 약학회지 (Jun, 1995)
저서 및 번역
  • [저서] 윤성화, 김인규, 김정한, 신대현, 조인호, 하현준, 노영쇠, 유기화학 (Morrison & Boyd - 6th Edition) (Mar, 1993)
특허 및 기타
  • [특허] 윤성화, 최동국 , 김인수, 박주영, 신경염증질환의 예방 또는 치료용 신규 화합물 및 이를 포함하는 약제학적 조성물 (출원) (10-2019-0143909) (Nov, 2019)
  • [특허] 윤성화, 박주영, 조덕연 , 최동국, 신경염증질환의 예방 또는 치료용 신규 화합물 및 이를 포함하는 약제학적 조성물 (출원) (10-2019-0143920) (Nov, 2019)
  • [특허] 윤성화, 최동국 , 김인수 , 박주영, 신규한 2-하이드록시-4-메틸벤조산 무수물 및 이를 유효성분으로 함유하는 신경염증질환의 예방 또는 치료용 조성물 (출원) (10-2019-0057102) (May, 2019)
  • [특허] 윤성화, 김승우, 이자경, 김수동, 박주영, 신경 보호 효과에 탁월한 신규한 물질로 할로알킬 살리실 산 유도체와 이의 약학적으로 허용 가능한 염 및 이를 유효 성분으로 함유하는 뇌질환의 치료 및 예방용 약제학적 조성물 (등록) (10-1167036) (Jul, 2012)
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